Proparacaine, from ally to enemy

report of a case of corneal perforation

Authors

DOI:

https://doi.org/10.70313/2718.7446.v18.n3.431

Keywords:

topical anesthetic, neurotrophic keratitis, corneal perforation, proparacaine, ophthalmic abuse

Abstract

Objective. To describe a case of neurotrophic keratitis with corneal perforation secondary to topical anesthetic abuse, emphasizing the importance of early diagnosis and patient education. 

Case report. A 34-year-old female presented with right eye pain and photophobia. She had been using topical proparacaine every 40 minutes, along with antibiotics and lubricants. Visual acuity was: OD count fingers at 3 meters; OS 7/10. Corneal perforation was diagnosed. Intensive antibiotic treatment, lubrication, atropine and conjunctival and tectonic patch coverage were performed. 

Conclusion. Unsupervised use of topical anesthetics can cause severe epithelial toxicity, progressive ulceration, and corneal perforation, as occurred in our case. Early detection and timely therapeutic intervention are essential to preserve ocular integrity.

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Author Biographies

  • Franco Battaglia , Hospital Privado de Comunidad

    Servicio de Oftalmología del Hospital Privado De La Comunidad, Mar Del Plata, Argentina 

  • Manuela Emilia Moreno , Hospital Privado de Comunidad

    Servicio de Oftalmología del Hospital Privado De La Comunidad, Mar Del Plata, Argentina 

  • Juan Diego Bravo-Almonacid , Hospital Privado de Comunidad

    Servicio de Oftalmología del Hospital Privado De La Comunidad, Mar Del Plata, Argentina 

  • Juan D. Bravo-Almonacid , Hospital Privado de Comunidad

    Servicio de Oftalmología del Hospital Privado De La Comunidad, Mar Del Plata, Argentina 

  • Ana Sofia Colucci , Hospital Privado de Comunidad

    Servicio de Oftalmología del Hospital Privado De La Comunidad, Mar Del Plata, Argentina 

  • Myriam Arguello , Hospital Privado de Comunidad

    Servicio de Oftalmología del Hospital Privado De La Comunidad, Mar Del Plata, Argentina 

  • Sergio Coppola , Hospital Privado de Comunidad

    Servicio de Oftalmología del Hospital Privado De La Comunidad, Mar Del Plata, Argentina 

References

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Published

2025-09-18

Issue

Section

Case Report

How to Cite

1.
Battaglia F, Moreno ME, Bravo-Almonacid JD, et al. Proparacaine, from ally to enemy: report of a case of corneal perforation. Oftalmol. clín. exp. 2025;18(3):e380-e388. doi:10.70313/2718.7446.v18.n3.431

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