Achados retinianos em paciente com glomerulonefrite proliferativa mesangial
DOI:
https://doi.org/10.70313/2718.7446.v18.n3.434Palavras-chave:
glomerulonefrite proliferativa mesangial, retinopatia, depósitos retinianos, drusasResumo
Objetivo: A glomerulonefrite proliferativa mesangial (GPM) é caracterizada pela proliferação de células mesangiais com acúmulo de matriz mesangial extracelular. O objetivo deste artigo é descrever os achados retinianos no fundo de olho de um paciente com GPM.
Caso clínico: Uma paciente de 34 anos apresentou-se para um check-up de rotina. Ela tinha histórico de asma brônquica, hipertensão arterial e GPM com depósitos de IgM, necessitando de transplante renal. Seu exame revelou uma acuidade visual de 10/10 em ambos os olhos. O exame de fundo revelou múltiplas lesões arredondadas medindo menos de um quarto do diâmetro papilar no polo posterior com envolvimento macular, lesões perifoveais e uma área retiniana periférica de 360°. A tomografia de coerência óptica revelou anormalidades do perfil posterior consistentes com depósitos drusenoides no nível do epitélio pigmentar da retina e múltiplas imagens hiperreflexivas devido a EPR alterado na retinofluoresceinografia. Estudos de campo visual também revelaram escotomas isolados em ambos os olhos e um eletrorretinograma normal.
Conclusão: Os achados retinianos na GPM fornecem informações sobre o envolvimento ocular na glomerulonefrite proliferativa mesangial e nos permitem monitorar esses pacientes para detecção precoce e/ou prevenção de potenciais complicações.
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