Conjunctival pigmented epithelioid melanocytoma
a case report
DOI:
https://doi.org/10.70313/2718.7446.v18.n3.437Keywords:
conjunctiva, pigmented epithelioid melanocytoma, magnocellular nevus, ocular surface tumor, corneaAbstract
Objective: To present a clinical case of conjunctival pigmented epithelioid melanocytoma and its therapeutic management with surgery and topical mitomycin C.
Case report: A 65-year-old female presented with accelerated growth of a pre-existing solid lesion in the right eye. Clinical examination revealed a pigmented conjunctival mass invading the corneal area, measuring 7.5 mm. After evaluation with ultrasound biomicroscopy, an excisional biopsy was performed using the no-touch technique, followed by four postoperative cycles of topical mitomycin C 0.04% applied every 6 hours for 7 days, with one-week rest intervals. Histopathological and immunohistochemical analysis confirmed pigmented epithelioid melanocytoma, an extremely rare condition in the ocular conjunctiva, with very few cases previously reported in the literature. At 5 months of ophthalmological and oncological follow-up, no recurrence was observed, and visual function remained preserved, with close monitoring maintained.
Conclusion: We describe a rare case of conjunctival pigmented epithelioid melanocytoma that was successfully treated and controlled locally. Additional cases will be necessary to further evaluate the potential role of adjuvant therapies such as topical mitomycin C.
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